NSBM Fall Meeting


Fall meeting – FINAL PROGRAMME

3D Protein Structures: what sequences cannot tell you

November 16th 2018


Venue: Boothzaal, University Library De Uithof, Utrecht


The Netherlands Society on Biomolecular Modelling (NSBM) is an independent society that brings people together in The Netherlands and beyond, that work on three dimensional structures of biomolecules and biomolecular simulations. This is a first announcement of our Fall meeting to which you are cordially invited. During the meeting, the floor will be given to students, PhD students, post-docs and a number of invited guest speakers who study protein structure and/or structural bioinformatics or related topics.

Location and dates

Lead contact



Final Programme

  • 09:30-10:00 Arrival and coffee
  • 10:00-10:05 Welcome word

Session I:

  • 10:05-10:50 Keynote I. Vlad Cojocaru, Hubrecht Insitute: “Molecular simulations of DNA recognition by transcription factors”
  • 10:50-11:10 Jan Huertas, MPI for Molecular Biomedicine, Germany: “Sequence-dependent nucleosome dynamics: Implications for transcription factor binding”
  • 11:10-11:30 Carlos Ramírez, University of Groningen: “In silico enzyme design of omega-transaminases”

Session II:

  • 11:30-12:15 Keynote II. Marc Baaden, Institut de Biologie Physico-Chimique: “3D protein structures in virtual molecular reality – insights from immersive visual exploration and touching molecules in motion”
  • 12:15-12:35 Attilio Vittorio Vargiu , Università di Cagliari, Italy: “Druggable protein conformations from enhanced-sampling of pocket volume and shape”

Lunch and posters

  • 12:35-14:00 Lunch, poster session, and VR demo

Session III:

  • 14:00-14:45 Keynote III. Chris Oostenbrink, Institute of Molecular Modeling and Simulation, BOKU Vienna, Austria: “Binding molecules in free-energy calculations”
  • 14:45-15:05 Janani Durairaj, Wageningen University & Research:“Structure-based Prediction of Sesquiterpene Synthase Product Specificity”
  • 15:05-15:25 Jan Walther Perthold, Institute of Molecular Modeling and Simulation, BOKU Vienna, Austria: “Automated Free Energy Calculation for Drug Design: Accelerated Enveloping Distribution Sampling”

Coffee break

  • 15:25-16:00 Coffee break

Session IV:

  • 16:00-16:20 Bogac Ercig, Sanquin: “From autoantibodies to therapeutics: en route to novel treatment for immune TTP”
  • 16:20-17:05 Keynote IV. Peter Peters, Maastricht University: “Beauty and Benefits of cryo-EM; our new endeavors in vitrification of proteins and cells”
  • 17:05 Closure & Poster/Presentation prize






Attendance is free of charge but registration is required.

Organized with the support of: