In a joint effort we wrote a review on the design of peptides for the inhibition of protein-protein interaction.

Today we learned the review is accepted for publication in Future Medicinal Chemistry.

Congrats to all involved!

Today Femke has started her work as a research assistent, bridging the time between het Bachelors’ degree and resuming education as a Master student in Aug 2019.

It’s great to have you in our team Femke, enjoy the coming time.

Today Joram has started his PhD, after having been with us first as a bachelor and then as a master student.

Glad to have you back Joram, looking forward to the next 4 years of research!!

At the European congress for Thrombosis and Haemostasis in Marseille, both Angelina and Johana recieved a prize for their outstanding abstracts and work.
Congratulations! It is well deserved!

Today we heard the paper on the role of CBL-b in atherosclerosis was accepted in the European Heart Journal !

Although Hessel and Gerry could only make a small contribution, we are very proud to be part of this teameffort for which all credits should go to Tom Seijkens and Esther Lutgens.

After a long struggle the application of TRAF-stops to promote organ acceptance after transplantation has been finally accepted for publication in “Immunity”.
A true collaborative study that could never have been performed by any of the individual labs involved.
1+1+1+1 = 10 !

glad to have made a humble contribution

Both Bogac and Johana held excellent presentations at the FEBS congress in beautiful Prague.
Great job!

Another nice comment was published on our JACC study, this time in Nature Reviews Cardiology

Today we heard that both Hessel and Bogac managed to have manuscripts accepted through collaborative studies we performed with the groups of Oliver Soehnlein in Munich and with Karen Vanhorelbeke in Kortrijk:

Chrono-pharmacological targeting of the CCL2-CCR2 axis ameliorates atherosclerosis
Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelmann, H., Schumski,A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G.A.F., Weber, C., Viola, J.R., Hidalgo, A., Scheiermann, C., Soehnlein, O.
to be published in Cell Metabolism

Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.
Schelpe A., Orlando C., Ercig B., Geeroms C., Pareyn I., Vandeputte N., Velásquez P., Leydi C.,  Roose E., Fostier K., Nicolaes G., Deckmyn H., De Meyer S., Vanhoorelbeke K., Jochmans K.
to be published in the European Journal of Haematology

great news of course, congratulations!!

Today the JACC paper on the use of small molecule inhibitors of TRAF6 to prevent and reduce atherosclerosis is out.

The journal has dedicated an editorial comment to it, closing with: the future is here, After 20 years of investigating the inflammatory hypothesis in the biology of atherosclerosis, the time to translate the experimental findings to humans may finally have come.