11-09-2018 Immunity paper accepted

After a long struggle the application of TRAF-stops to promote organ acceptance after transplantation has been finally accepted for publication in “Immunity”.
A true collaborative study that could never have been performed by any of the individual labs involved.
1+1+1+1 = 10 !

glad to have made a humble contribution

Continue Reading

02-05-2018 Two papers in one day!

Today we heard that both Hessel and Bogac managed to have manuscripts accepted through collaborative studies we performed with the groups of Oliver Soehnlein in Munich and with Karen Vanhorelbeke in Kortrijk:

Chrono-pharmacological targeting of the CCL2-CCR2 axis ameliorates atherosclerosis
Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelmann, H., Schumski,A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G.A.F., Weber, C., Viola, J.R., Hidalgo, A., Scheiermann, C., Soehnlein, O.
to be published in
Cell Metabolism

Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.
Schelpe A., Orlando C., Ercig B., Geeroms C., Pareyn I., Vandeputte N., Velásquez P., Leydi C.,  Roose E., Fostier K., Nicolaes G., Deckmyn H., De Meyer S., Vanhoorelbeke K., Jochmans K.
to be published in the European Journal of Haematology

great news of course, congratulations!!

Continue Reading

06-02-2018 JACC paper on TRAF-STOPS out

Today the JACC paper on the use of small molecule inhibitors of TRAF6 to prevent and reduce atherosclerosis is out.

The journal has dedicated an editorial comment to it, closing with: the future is here, After 20 years of investigating the inflammatory hypothesis in the biology of atherosclerosis, the time to translate the experimental findings to humans may finally have come.

Continue Reading